| Software | File Extention |
| Audio/Video Interleaved | .avi |
| Chem 3D | .c3d |
| ChemDraw | .cdx |
| Chemical Markup Language | .cml |
| Chemical Structure | .xyz |
| Chemical Structure | .xyz |
| Chemical Structure Markup Language | .csml |
| Chemwindow | .cwg |
| Crystallographic Information File | .cif |
| IsisDraw | .skc |
| JCAMP-DX | .jdx |
| Microsoft Excel | .xls, .xlsx |
| Microsoft Word | .doc, .docx, .dot, .rtf |
| Mol File | .mol |
| Moving Picture Experts Group | .mpg |
| MPEG-4 Part 14 | .mp4 |
| Plain Text | .txt |
| Portable Document Format | .pdf |
| PowerPoint | .ppt, .pptx |
| Protein Data Bank | .pdb |
| Quicktime | .qt, .mov |
| Rich Text Format | .rtf |
| Tagged Image File Format | .tif |
| TeX/LaTeX/REVTeX | .tex |
| Virtual Reality Modeling Language | .vrml |
| Word Perfect | .wp, .wpd, .rtf |